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Article

Genetic association of the activin A receptor gene (ACVR2A) and pre-eclampsia.

Molecular human reproduction - 1 Mar 2009

Fitzpatrick E, Johnson M P, Dyer T D, Forrest S, Elliott K, Blangero J, Brennecke S P, Moses E K

Abstract excerpt

Pre-eclampsia is a common serious disorder of human pregnancy, which is associated with significant maternal and perinatal morbidity and mortality. The suspected aetiology of pre-eclampsia is complex, with susceptibility being attributable to multiple environmental factors and a large genetic component. Recently, we reported significant linkage to chromosome 2q22 in 34 Australian/New Zealand (Aust/NZ)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19126782
DOI: 10.1093/molehr/gap001
PMCID: PMC2647107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic association of the activin A receptor gene (ACVR2A) and pre-eclampsia.PMID 19126782Read ↗

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Targeted sequencing analysis of ACVR2A gene identifies novel risk variants associated with preeclampsia.Semantic proximity Read ↗

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ACVR2A Facilitates Trophoblast Cell Invasion through TCF7/c-JUN Pathway in Pre-eclampsia ProgressionSemantic proximity Read ↗

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A genome scan in families from Australia and New Zealand confirms the presence of a maternal susceptibility locus for pre-eclampsia, on chromosome 2.Semantic proximity Read ↗

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