Article
RAIDD expression is impaired in multidrug resistant osteosarcoma cell lines.
Cancer chemotherapy and pharmacology - 1 Aug 2009
Yang Cao, Hornicek Francis J, Wood Kirkham B, Schwab Joseph H, Mankin Henry, Duan Zhenfeng
Abstract excerpt
PURPOSE: To identify the apoptosis genes involved in the multidrug resistant phenotype of osteosarcoma. METHODS: Multidrug resistant human osteosarcoma cell line (U-2 OS MR) and a drug sensitive parental cell line (U-2 OS) were both treated with paclitaxel and analyzed by the gene array containing 96 apoptosis associated genes. The different expression of the special apoptosis associated genes were further...
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