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Article

Rel A Is an Independent Biomarker of Clinical Outcome in Chronic Lymphocytic Leukemia

6 Jan 2009

Abstract excerpt

PURPOSE: We recently demonstrated the biologic importance of the nuclear factor kappa B (NF-kappaB) subunit Rel A in chronic lymphocytic leukemia (CLL) and hypothesized that Rel A DNA binding would have prognostic significance in this disease. PATIENTS AND METHODS: Rel A DNA binding was quantified in nuclear extracts derived from 131 unselected CLL patient samples using a quantitative DNA-binding enzyme-linked...

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PMID: 19124804
DOI: 10.1200/jco.2008.19.1114

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