Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Serum TK levels in CLL identify Binet stage A patients within biologically defined prognostic subgroups most likely to undergo disease progression.

European journal of haematology - 1 Oct 2006

Matthews Christine, Catherwood Mark A, Morris T C M, Kettle Paul J, Drake Mary B, Gilmore William S, Alexander H Denis

Abstract excerpt

OBJECTIVE: Serum thymidine kinase (TK) levels have been shown to be correlated with survival in many malignancies, including chronic lymphocytic leukaemia (CLL). This study was designed to investigate associations between TK levels and other prognostic markers, in newly and previously diagnosed B...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADP-ribosyl Cyclase 1
Share to Chromosome Aberrations
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flow Cytometry

Share to Immunoglobulin Variable Region

Share to In Situ Hybridization, Fluorescence

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Thymidine Kinase

Source

Identifiers

PMID: 16856923
DOI: 10.1111/j.1600-0609.2006.00707.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16856923-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Serum TK levels in CLL identify Binet stage A patients within biologically defined prognostic subgroups most likely to undergo disease progression.PMID 16856923Read ↗

Defining the prognosis of early stage chronic lymphocytic leukaemia patients.Semantic proximity Read ↗

Definition of progression risk based on combinations of cellular and molecular markers in patients with Binet stage A chronic lymphocytic leukaemia.Semantic proximity Read ↗

Binet's staging system and VH genes are independent but complementary prognostic indicators in chronic lymphocytic leukemia.Semantic proximity Read ↗

Clinical and molecular predictors of disease severity and survival in chronic lymphocytic leukemiaSemantic proximity Read ↗

Patients with chronic lymphocytic leukemia with mutated VH genes presenting with Binet stage B or C form a subgroup with a poor outcome.Semantic proximity Read ↗

A subset of Binet stage A CLL patients with TP53 abnormalities and mutated IGHV genes have stable diseaseSemantic proximity Read ↗

Predicting Stage Progression in Binet Stage a Chronic Lymphocytic Leukemia.Semantic proximity Read ↗

CD38 expression level and pattern of expression remains a reliable and robust marker of progressive disease in chronic lymphocytic leukemia.Semantic proximity Read ↗

Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia.Semantic proximity Read ↗

Do biologic parameters affect the time to first treatment of clinical monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia Rai stage 0? Results of a prospective analysis.Semantic proximity Read ↗

CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease.Semantic proximity Read ↗

Immunoglobulin light chain mutational status refines IGHV prognostic value in identifying chronic lymphocytic leukemia patients with early treatment requirement.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.