Article
MUC1 568 A/G genotype-dependent cancer antigen 15-3 levels in breast cancer patients.
Clinical biochemistry - 1 May 2009
Kruit Adrian, Tilanus-Linthorst Madeleine M, Boonstra Joke G, van Schaik Ron H N, Grutters Jan C, van den Bosch Jules M M, Ruven Henk J T
Abstract excerpt
OBJECTIVES: CA 15-3 is a widely used tumor marker for breast cancer. We have investigated whether the MUC1 568 A/G polymorphism can influence CA 15-3 levels in healthy women and patients with breast tumors. DESIGN AND METHODS: CA 15-3 was measured in 208 healthy women, in 67 with benign disease, and in 162 women with breast cancer. All subjects were genotyped for the MUC1 568 A/G polymorphism. RESULTS:...
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