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Article

IFN-alpha can both protect against and promote the development of type 1 diabetes.

Annals of the New York Academy of Sciences - 1 Dec 2008

Wong F Susan, Wen Li

Abstract excerpt

Viral infection has been hypothesized to be one of the environmental triggers for the development of type 1 diabetes. Infection induces a large amount of interferon-alpha (IFN-alpha) produced by dendritic cells and other cells. To test the role of IFN-alpha in the development of diabetes, we have used three different experimental approaches in both diabetes-prone and -resistant animal models for type 1 diabetes....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19120292
DOI: 10.1196/annals.1447.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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