Article
Novel markers of inflammation identified in tumor necrosis factor receptor-associated periodic syndrome (TRAPS) by transcriptomic analysis of effects of TRAPS-associated tumor necrosis factor receptor type I mutations in an endothelial cell line.
Arthritis and rheumatism - 1 Jan 2009
Rebelo Susana L, Amel-Kashipaz Mohammad R, Radford Paul M, Bainbridge Susan E, Fiets Roel, Fang Johnny, McDermott Elizabeth M, Powell Richard J, Todd Ian, Tighe Patrick J
Abstract excerpt
OBJECTIVE: To analyze the effects of tumor necrosis factor receptor-associated periodic syndrome (TRAPS)-associated mutant tumor necrosis factor receptor type I (TNFRI) expression in a cell type directly relevant to the inflammation in TRAPS, and to identify novel markers associated with mutant TNFRI expression. METHODS: Transcriptome analysis on 30,000 human genes was performed on SK-Hep-1 human endothelial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.