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Gene expression profiling of human mesenchymal stem cells derived from bone marrow during expansion and osteoblast differentiation

12 Mar 2007

Abstract excerpt

BACKGROUND: Human mesenchymal stem cells (MSC) with the capacity to differentiate into osteoblasts provide potential for the development of novel treatment strategies, such as improved healing of large bone defects. However, their low frequency in bone marrow necessitate ex vivo expansion for further clinical application. In this study we asked if MSC are developing in an aberrant or unwanted way during ex vivo...

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PMID: 17352823
DOI: 10.1186/1471-2164-8-70

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