Article
Mild electrical stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling.
PloS one - 1 Jan 2008
Morino Saori, Kondo Tatsuya, Sasaki Kazunari, Adachi Hironori, Suico Mary Ann, Sekimoto Erika, Matsuda Tomoko, Shuto Tsuyoshi, Araki Eiichi, Kai Hirofumi
Abstract excerpt
Low-intensity electrical current (or mild electrical stimulation; MES) influences signal transduction and activates phosphatidylinositol-3 kinase (PI3K)/Akt pathway. Because insulin resistance is characterized by a marked reduction in insulin-stimulated PI3K-mediated activation of Akt, we asked whether MES could increase Akt phosphorylation and ameliorate insulin resistance. In addition, it was also previously...
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