Article
Lack of influence of glutathione S-transferase genotype profile on cancer susceptibility in smokers and nonsmokers.
Medical science monitor : international medical journal of experimental and clinical research - 1 Jan 2009
Sampaio Aline Castaldi, Morari Elaine Cristina, Bufalo Natassia Elena, Leite Janaina Luisa, Lima Carmen Silvia Passos, Ward Laura S
Abstract excerpt
BACKGROUND: The glutathione-S-transferase (GST) gene family has an important role in the biotransformation and detoxification of different xenobiotics and endogenous carcinogens. GST profile has been associated to an increased risk for several types of tumors in different populations, but ethnic stratification makes data interpretation difficult. The Brazilian population represents a unique model in which the...
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