Article
CD4 cell-guided scheduled treatment interruptions in HIV-infected patients with sustained immunologic response to HAART.
AIDS (London, England) - 27 Apr 2009
Maggiolo Franco, Airoldi Monica, Callegaro Annapaola, Martinelli Canio, Dolara Alberto, Bini Teresa, Gregis Giampietro, Quinzan Giampaolo, Ripamonti Diego, Ravasio Veronica, Suter Fredy
Abstract excerpt
OBJECTIVE: To compare continuous HAART with a CD4 cell-driven scheduled treatment interruption (STI) strategy. METHODS: LOng Term Treatment Interruption study is a randomized, controlled, prospective trial. Patients with CD4 cell counts more than 700 cells/microl were eligible, and the immunologic threshold to resume HAART was 350 cells/microl. The primary end point was the development of an opportunistic...
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