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Article

Rhabdovirus Matrix Protein Structures Reveal a Novel Mode of Self-Association

26 Dec 2008

Abstract excerpt

The matrix (M) proteins of rhabdoviruses are multifunctional proteins essential for virus maturation and budding that also regulate the expression of viral and host proteins. We have solved the structures of M from the vesicular stomatitis virus serotype New Jersey (genus: Vesiculovirus) and from Lagos bat virus (genus: Lyssavirus), revealing that both share a common fold despite sharing no identifiable sequence...

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PMID: 19112510
DOI: 10.1371/journal.ppat.1000251

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