Article
Adenovirus E1A regulates lung epithelial ICAM-1 expression by interacting with transcriptional regulators at its promoter.
American journal of physiology. Lung cellular and molecular physiology - 1 Mar 2009
Morimoto Kiyoshi, Gosselink John, Kartono Aileen, Hogg James C, Hayashi Shizu, Ogawa Emiko
Abstract excerpt
We focused on the regulation of inflammatory mediator expression by adenovirus E1A in lung epithelial cells and the role of this viral protein in the pathogenesis of chronic obstructive pulmonary disease (COPD). We previously reported that E1A, a well-known regulator of host genes, increased ICAM...
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