Article
Association of parental hyperhomocysteinemia and C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism with recurrent pregnancy loss.
Clinical biochemistry - 1 Mar 2009
Govindaiah Vinukonda, Naushad Shaik Mohammad, Prabhakara Krishnamurthy, Krishna Prasad Chintakindi, Radha Rama Devi Akella
Abstract excerpt
OBJECTIVES: To investigate the association of parental hyperhomocysteinemia, C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism and DNA damage with recurrent pregnancy loss (RPL). DESIGN AND METHODS: A case-control study. Reverse phase HPLC, PCR-RFLP and Cytokinesis blocked micronuclei assay were used to assess total plasma homocysteine, C677T MTHFR polymorphism and DNA damage respectively. Student...
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