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Article

Association study between methylenetetrahydrofolate reductase polymorphisms and unexplained recurrent pregnancy loss: a meta-analysis.

Gene - 10 Feb 2013

Cao Yunlei, Xu Jianhua, Zhang Zhaofeng, Huang Xianliang, Zhang Aiping, Wang Jian, Zheng Qiupeng, Fu Lingyuan, Du Jing

Abstract excerpt

BACKGROUND: Recurrent pregnancy loss is an important clinical problem. Recently, high-level homocysteine in blood has been considered as a possible cause. Genetic polymorphisms in methylenetetrahydrofolate reductase (MTHFR) have been proved to be the common hereditary factors of high-level homocysteine. The association between MTHFR polymorphisms and unexplained recurrent pregnancy loss (URPL) has been reported...

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Source

Identifiers

PMID: 23201418
DOI: 10.1016/j.gene.2012.10.091

Genes

MTHFR

Variants

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