Article
Methylenetetrahydrofolate reductase C677T and A1298C polymorphism and changes in homocysteine concentrations in women with idiopathic recurrent pregnancy losses.
Reproduction (Cambridge, England) - 1 Feb 2006
Mtiraoui N, Zammiti W, Ghazouani L, Braham N Jmili, Saidi S, Finan R R, Almawi W Y, Mahjoub T
Abstract excerpt
Because they have been described as strong risk factors for idiopathic recurrent pregnancy losses (RPLs), we assessed the association between the methylenetetrahydrofolate reductase (MTHFR) single-nucleotide polymorphisms (SNPs) C677T and A1298C and hyperhomocysteinemia in Tunisian women with idiopathic RPL. Study subjects comprised 200 patients with more than three consecutive RPLs, and 200 age-matched parous...
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