Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Peripheral blood gene expression profile associated with sustained virologic response after peginterferon plus ribavirin therapy for chronic hepatitis-C genotype 1.

Journal of the National Medical Association - 1 Dec 2008

Huang Chao, Chen Hegang, Cassidy William, Howell Charles D

Abstract excerpt

We investigated the relationship between global gene expression in peripheral blood mononuclear cells (PBMCs) during the first 4 weeks of peginterferon alfa and ribavirin therapy and long-term eradication of hepatitis-C genotype 1 infections in 23 patients. A sustained virologic response (SVR), defined as an undetected serum HCV ribonucleic acid (RNA) at week 72, was the virologic response endpoint. PBMC RNA was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepacivirus
Share to Hepatitis C

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interferon-alpha

Share to Interferon alpha-2

Share to Leukocytes, Mononuclear

Share to Oligonucleotide Array Sequence Analysis

Share to Polyethylene Glycols

Share to Ribavirin

Source

Identifiers

PMID: 19110910
DOI: 10.1016/s0027-9684(15)31542-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Peripheral blood gene expression profile associated with sustained virologic response after peginterferon plus ribavirin therapy for chronic hepatitis-C genotype 1.PMID 19110910Read ↗

Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy.Semantic proximity Read ↗

Peripheral Blood Mononuclear Cell Gene Expression Remains Broadly Altered Years after Successful Interferon-Based Hepatitis C Virus TreatmentSemantic proximity Read ↗

Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment responseSemantic proximity Read ↗

Early gene expression profiles of patients with chronic hepatitis C treated with pegylated interferon‐alfa and ribavirin†Semantic proximity Read ↗

Gene Expression Profiling To Predict and Assess the Consequences of Therapy-Induced Virus Eradication in Chronic Hepatitis C Virus InfectionSemantic proximity Read ↗

Hepatic gene expression and prediction of therapy response in chronic hepatitis C patients.Semantic proximity Read ↗

Interferon-stimulated genes are associated with peginterferon/ribavirin treatment response regardless of IL28B alleles in hepatitis C virus/HIV-coinfected patients.Semantic proximity Read ↗

Peripheral blood correlates of virologic relapse after Sofosbuvir and Ribavirin treatment of Genotype-1 HCV infection.Semantic proximity Read ↗

Peripheral blood mononuclear cells microRNA predicts treatment outcome of hepatitis C virus genotype 1 infection.Semantic proximity Read ↗

Liver Gene Expression Profiles Correlate with Virus Infection and Response to Interferon Therapy in Chronic Hepatitis B PatientsSemantic proximity Read ↗

Interferon Alfa Regulated Gene Expression in Patients Initiating Interferon Treatment for Chronic Hepatitis CSemantic proximity Read ↗

Hepatic Toll-Like Receptor 3 expression in chronic hepatitis C genotype 1 correlates with treatment response to peginterferon plus ribavirin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.