Article
Quantification of genomic mutations in murine hematopoietic cells.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Geiger Hartmut, David Schleimer, Nattamai Kalpana J, Jan Vijg
Abstract excerpt
Maintaining the stability of the genome is critical to cell survival and normal cell growth. Genetic modification of hematopoietic cells might bear an inherent increased risk for the accumulation of DNA mutations. It frequently requires cultivation of the cells under super-physiological oxygen le...
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