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Article

Simulation of DNA sequence evolution under models of recent directional selection.

Briefings in bioinformatics - 1 Jan 2009

Kim Yuseob, Wiehe Thomas

Abstract excerpt

Computer simulation is an essential tool in the analysis of DNA sequence variation for mapping events of recent adaptive evolution in the genome. Various simulation methods are employed to predict the signature of selection in sequence variation. The most informative and efficient method currently in use is coalescent simulation. However, this method is limited to simple models of directional selection....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19109303
DOI: 10.1093/bib/bbn048
PMCID: PMC2638626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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