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Article

Differential gene repertoire in Mycobacterium ulcerans identifies candidate genes for patho-adaptation.

PLoS neglected tropical diseases - 1 Jan 2008

Käser Michael, Pluschke Gerd

Abstract excerpt

BACKGROUND: Based on large genomic sequence polymorphisms, several haplotypes belonging to two major lineages of the human pathogen Mycobacterium ulcerans could be distinguished among patient isolates from various geographic origins. However, the biological relevance of insertional/deletional diversity is not understood. METHODOLOGY: Using comparative genomics, we have investigated the genes located in regions of...

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Identifiers

PMID: 19104652
DOI: 10.1371/journal.pntd.0000353
PMCID: PMC2600814

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