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The significance of M1 macrophage should be highlighted in peripheral nerve regeneration.

Histology and histopathology - 1 Sept 2023

Feng Ruiqin, Zhang Peixun

Abstract excerpt

Macrophage influences peripheral nerve regeneration. According to the classical M1/M2 paradigm, the M1 macrophage is an inhibitor of regeneration, while the M2 macrophage is a promoter. However, several studies have shown that M1 macrophages are indispensable for peripheral nerve repair and facilitate many critical processes in axonal regeneration. In this review, we summarized the information on macrophage...

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PMID: 36734334
DOI: 10.14670/HH-18-591

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