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Article

Cdc42-mTOR signaling pathway controls Hes5 and Pax6 expression in retinoic acid-dependent neural differentiation.

The Journal of biological chemistry - 20 Feb 2009

Endo Makoto, Antonyak Marc A, Cerione Richard A

Abstract excerpt

The conditional knockout of the small GTPase Cdc42 from neuroepithelial (NE) and radial glial (RG) cells in the mouse telencephalon has been shown to have a significant impact on brain development by causing these neural progenitor cells to detach from the apical/ventricular surface and to lose their cell identity. This has been attributed to the requirement for Cdc42 in establishing proper apical/basal cell...

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Source

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Identifiers

PMID: 19097998
DOI: 10.1074/jbc.M807745200
PMCID: PMC3837441

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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