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Article

Genomic copy number alterations with transcriptional deregulation at 6p identify an aggressive HCC phenotype.

Carcinogenesis - 1 Jul 2013

Kwon So Mee, Kim Dong-Sik, Won Nam Hee, Park Soo Jeong, Chwae Yong-Joon, Kang Ho Chul, Lee Soo Hwan, Baik Eun Joo, Thorgeirsson Snorri S, Woo Hyun Goo

Abstract excerpt

Genomic analyses have revealed the enormous heterogeneity in essentially all cancer types. However, the identification of precise subtypes, which are biologically informative and clinically useful, remains a challenge. The application of integrative analysis of multilayered genomic profiles to define the chromosomal regions of genomic copy number alterations with concomitant transcriptional deregulation is...

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Share to Apoptosis Regulatory Proteins
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 6

Share to Comparative Genomic Hybridization

Share to DNA Copy Number Variations

Share to Hep G2 Cells

Share to Liver Neoplasms

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Source

Identifiers

PMID: 23508637
DOI: 10.1093/carcin/bgt095

Genes

IER3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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