Article
Differences in a Single Extracellular Residue Underlie Adhesive Functions of Two Zebrafish Aqp0s.
Cells - 6 Aug 2021
Vorontsova Irene, Hall James E, Schilling Thomas F, Nagai Noriaki, Nakazawa Yosuke
Abstract excerpt
Aquaporin 0 (AQP0) is the most abundant lens membrane protein, and loss of function in human and animal models leads to cataract formation. AQP0 has several functions in the lens including water transport and adhesion. Since lens optics rely on strict tissue architecture achieved by compact cell-to-cell adhesion between lens fiber cells, understanding how AQP0 contributes to adhesion would shed light on normal...
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