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Article

Aggregate formation and toxicity by wild-type and R621C synphilin-1 in the nigrostriatal system of mice using adenoviral vectors.

Journal of neurochemistry - 1 Jan 2009

Krenz Antje, Falkenburger Björn H, Gerhardt Ellen, Drinkut Anja, Schulz Jörg B

Abstract excerpt

Synphilin-1 was described as a protein interacting with alpha-synuclein and is commonly found in Lewy bodies, the pathological hallmark of Parkinson's disease (PD). Our group has previously described and characterized in vitro a mutation in the synphilin-1 gene (R621C) in PD patients. Providing t...

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Identifiers

PMID: 19094062
DOI: 10.1111/j.1471-4159.2008.05755.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19094062-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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