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Article

SETD2 epidermal deficiency promotes cutaneous wound healing via activation of AKT/mTOR Signalling

5 May 2021

Abstract excerpt

OBJECTIVES: Cutaneous wound healing is one of the major medical problems worldwide. Epigenetic modifiers have been identified as important players in skin development, homeostasis and wound repair. SET domain-containing 2 (SETD2) is the only known histone H3K36 tri-methylase; however, its role in skin wound healing remains unclear. MATERIALS AND METHODS: To elucidate the biological role of SETD2 in wound healing,...

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PMID: 33949020
DOI: 10.1111/cpr.13045

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