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Article

Developmental function of Elf-1: an essential transcription factor during embryogenesis in Drosophila.

Genes & development - 1 Sept 1991

Bray S J, Kafatos F C

Abstract excerpt

The Drosophila transcription factor Elf-1 binds to a cis-acting element that is essential for neuronal expression of the Dopa decarboxylase gene (Ddc). Elf-1 also stimulates transcription from the Ddc and Ultrabithorax promoters in vitro. To investigate the function of this factor in vivo we have screened for mutations and identified the Elf-1 gene as grainyhead (grh), a previously known embryonic lethal locus....

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PMID: 1909284
DOI: 10.1101/gad.5.9.1672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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