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[BRCA1/2 gene mutation in Chinese familial breast cancer patients: a multi-center report of 115 cases].

Zhonghua yi xue za zhi - 9 Sept 2008

Hu Zhen, Li Wen-Feng, Liu Xiao-Yi, Zhang Bin, Cao Ming-Zhi, Wang Yong-Sheng, Zhao Lin, Song Chuan-Gui, Lu Jin-Song, Wu Jiong, DI Gen-Hong, Shen Kun-Wei, Han Qi-Xia, Shen Zhen-Zhou, Huang Wei, Shao Zhi-Min

Abstract excerpt

OBJECTIVE: To study the BRCA1/2 gene mutation frequency and characteristics in Chinese familial breast cancer patients. METHODS: Denaturing high-performance liquid chromatography (DHPLC) and following DNA sequencing in BRCA1/2 gene whole coding region and exon-intron splicing sites were performed in the specimens obtained during operation from 115 probands of familial breast cancer from 4 breast cancer centers in...

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Age of Onset
Asian People
Breast Neoplasms
China
BRCA2 gene

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PMID: 19087709

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BRCA1
BRCA2

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