Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human inhibitor of growth 1 inhibits hepatoma cell growth and influences p53 stability in a variant-dependent manner.

Hepatology (Baltimore, Md.) - 1 Feb 2009

Zhu Zhi, Luo Zhigang, Li Yongmei, Ni Canrong, Li Honghua, Zhu Minghua

Abstract excerpt

UNLABELLED: Inhibitor of growth 1 (ING1) is a type II tumor suppressor that affects cell function by altering chromatin structure and regulating transcription. Recently, three ING1 splice variants have been cloned, but their roles in apoptosis and p53 regulation in human hepatocellular carcinoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Chromosomes, Human, Pair 13
Share to Genes, Reporter

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Liver Neoplasms

Share to Mice, Nude

Share to Proto-Oncogene Proteins c-mdm2

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 19085961
DOI: 10.1002/hep.22675

Genes

ING1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19085961-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human inhibitor of growth 1 inhibits hepatoma cell growth and influences p53 stability in a variant-dependent manner.PMID 19085961Read ↗

Insulin-Like Growth Factor 2 mRNA-Binding Protein 1 (IGF2BP1) Is an Important Protumorigenic Factor in Hepatocellular CarcinomaSemantic proximity Read ↗

The role of the tumour suppressor p33 ING1b in human neoplasia.Semantic proximity Read ↗

No ING1 mutations in human brain tumours but reduced expression in high malignancy grades of astrocytoma.Semantic proximity Read ↗

Block of proliferation 1 (BOP1) plays an oncogenic role in hepatocellular carcinoma by promoting epithelial-to-mesenchymal transitionSemantic proximity Read ↗

Allele-specific imbalance of oxidative stress-induced growth inhibitor 1 associates with progression of hepatocellular carcinoma.Semantic proximity Read ↗

PAIP1 is a Novel Oncogene in Human Hepatocellular CarcinomaSemantic proximity Read ↗

Expression profiles of mRNA transcript variants encoding the human inhibitor of growth tumor suppressor gene family in normal and neoplastic tissues.Semantic proximity Read ↗

Inhibitor of growth tumor suppressors in cancer progression.Semantic proximity Read ↗

Downregulation of nuclear expression of the p33 <sup>ING1b</sup> inhibitor of growth protein in invasive carcinoma of the breastSemantic proximity Read ↗

ALDH1A1-overexpressing cells are differentiated cells but not cancer stem or progenitor cells in human hepatocellular carcinoma.Semantic proximity Read ↗

STAT1 inhibits human hepatocellular carcinoma cell growth through induction of p53 and Fbxw7Semantic proximity Read ↗

Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.