Article
CYP2A6 genotypes and coumarin-oxidation phenotypes in a Thai population and their relationship to tobacco smoking.
European journal of clinical pharmacology - 1 Apr 2009
Mahavorasirikul Wiratchanee, Tassaneeyakul Wichittra, Satarug Soisagwan, Reungweerayut Ronnatrai, Na-Bangchang Chacrin, Na-Bangchang Kesara
Abstract excerpt
OBJECTIVE: To investigate the association between polymorphisms in the human CYP2A6 gene, CYP2A6 enzyme activity and the influence of cigarette smoking in a Thai population. METHODS: Coumarin (5 mg capsule) was administered to 194 healthy Thai subjects. Genetic variation of the CYP2A6 gene was id...
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