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Article

Phenotypic integration of skeletal traits during growth buffers genetic variants affecting the slenderness of femora in inbred mouse strains.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2009

Jepsen Karl J, Hu Bin, Tommasini Steven M, Courtland Hayden-William, Price Christopher, Cordova Matthew, Nadeau Joseph H

Abstract excerpt

Compensatory interactions among adult skeletal traits are critical for establishing strength but complicate the search for fracture susceptibility genes by allowing many genetic variants to exist in a population without loss of function. A better understanding of how these interactions arise during growth will provide new insight into genotype-phenotype relationships and the biological controls that establish...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19082857
DOI: 10.1007/s00335-008-9158-1
PMCID: PMC2650248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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