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Article

Noninvasive Test for Mitochondrial DNA A1555G Mutation Associated with Deafness.

Clinical laboratory - 1 Jan 2017

Fan Wenlu, Zhu Yi, Tang Xiaowen, Xue Ling

Abstract excerpt

BACKGROUND: The homoplasmic mitochondrial DNA (mtDNA) A1555G mutation in the highly conserved decoding site of 12S rRNA has been associated with aminoglycoside-induced and nonsyndromic hearing loss in many families worldwide. The A1555G mutation detection is an important part of hearing screening. At present, blood samples are the most common source of genomic DNA. However, drawing blood is invasive for...

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Identifiers

PMID: 28164482
DOI: 10.7754/Clin.Lab.2016.160709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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