Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variations in mouse mitochondrial DNA copy number from fertilization to birth are associated with oxidative stress.

Reproductive biomedicine online - 1 Dec 2008

Aiken Catherine Em, Cindrova-Davies Tereza, Johnson Martin H

Abstract excerpt

Mitochondria are inherited maternally via the oocyte, which in the mouse contains 150-250 x 10(3) copies of mitochondrial DNA (mtDNA). The number of mtDNA copies/embryo is thought to be stable during cleavage, being progressively diluted/cell with each round of cell division, until replication be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Blotting, Western
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fertilization

Share to Oxidative Stress

Share to Pregnancy

Share to Pregnancy, Animal

Share to Superoxide Dismutase

Source

Identifiers

PMID: 19079965
DOI: 10.1016/s1472-6483(10)60409-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19079965-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variations in mouse mitochondrial DNA copy number from fertilization to birth are associated with oxidative stress.PMID 19079965Read ↗

The Role of Mitochondrial DNA Copy Number in Mammalian Fertility1Semantic proximity Read ↗

Dynamic comparisons of high-resolution expression profiles highlighting mitochondria-related genes betweenin vivoandin vitrofertilized early mouse embryosSemantic proximity Read ↗

Epigenetic and experimental modifications in early mammalian development: Part I: Mitochondria: potential roles in embryogenesis and nucleocytoplasmic transferSemantic proximity Read ↗

Role of the mitochondrial genome in preimplantation development and assisted reproductive technologiesSemantic proximity Read ↗

Mitochondrial genome undergoes de novo DNA methylation that protects mtDNA against oxidative damage during the peri-implantation windowSemantic proximity Read ↗

Transmission, inheritance and replication of mitochondrial DNA in mammals: implications for reproductive processes and infertilitySemantic proximity Read ↗

The role of the mtDNA set point in differentiation, development and tumorigenesis.Semantic proximity Read ↗

Mitochondrial DNA copy number as a predictor of embryo viabilitySemantic proximity Read ↗

Mutation dependance of the mitochondrial DNA copy number in the first stages of human embryogenesis.Semantic proximity Read ↗

Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA.Semantic proximity Read ↗

DNA methylation dynamics in mouse preimplantation embryos revealed by mass spectrometrySemantic proximity Read ↗

A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.