Article
Population genetics and comparative genetics of CLDN1, a gene involved in hepatitis C virus entry.
Human heredity - 1 Jan 2009
Bekker Vincent, O'Brien Thomas R, Chanock Stephen
Abstract excerpt
The claudin-1 gene (CLDN1) is a member of a family of genes that encodes proteins found in tight junctions and it has recently been implicated as one of several receptors for late stage binding of hepatitis C virus (HCV). Exploration of the population genetics of this gene could be informative, especially in the investigation of a possible genetic contribution to HCV infection. Comparison to a highly similar...
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