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Article

Genetic variation in CLDN1 and susceptibility to hepatitis C virus infection.

Journal of viral hepatitis - 1 Mar 2010

Bekker V, Chanock S J, Yeager M, Hutchinson A A, von Hahn T, Chen S, Xiao N, Dotrang M, Brown M, Busch M P, Edlin B R, Rice C M, O'Brien T R

Abstract excerpt

Claudin-1 is a recently discovered co-receptor for hepatitis C virus (HCV) that is required for late-stage binding of the virus. Because variants in the gene that encodes claudin-1 (CLDN1) could play a role in HCV infection, we conducted a 'whole gene association study' among injection drug users (IDUs) to examine whether CLDN1 genetic variants were associated with the risk of HCV infection or with viral...

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Source

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Identifiers

PMID: 19674288
DOI: 10.1111/j.1365-2893.2009.01166.x
PMCID: PMC2921226

Genes

CLDN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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