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Article

Mitochondrial polymorphisms are associated both with increased and decreased longevity.

Human heredity - 1 Jan 2009

Castri Loredana, Melendez-Obando Mauricio, Villegas-Palma Ramon, Barrantes Ramiro, Raventos Henrieta, Pereira Reynaldo, Luiselli Donata, Pettener Davide, Madrigal Lorena

Abstract excerpt

Previous work compared frequency of longevity-associated polymorphisms (LAPS) in long-lived individuals and in controls from the general population (primarily in Europe and Japan), suggesting the polymorphisms are responsible for unusual longevity. However, individuals from the general population are not the control group for long-lived subjects because both were born in different periods. We report results of a...

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Identifiers

PMID: 19077432
DOI: 10.1159/000181152
PMCID: PMC2868917

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