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Article

Characterization of the promoter region of the human PARG gene and its response to PU.1 during differentiation of HL-60 cells.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Dec 2008

Uchiumi Fumiaki, Sakakibara Gakushi, Sato Junko, Tanuma Sei-ichi

Abstract excerpt

The metabolism of poly(ADP-ribose) plays important roles in the nuclear function of mammalian cells. Previously, we analyzed expression of the poly(ADP-ribose) glycohydrolase (PARG) gene during HL-60 cell differentiation and found that expression was greatly reduced by 4 h after 12-O-tetradecanoyl-phorbol-13-acetate (TPA) treatment and returned to the initial level within 20 h. In the present study, a 2.1-kb...

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Identifiers

PMID: 19076642
DOI: 10.1111/j.1365-2443.2008.01240.x

Genes

PARG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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