Article
Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network.
Human molecular genetics - 1 Mar 2009
Rogne Marie, Stokka Anne Jorunn, Taskén Kjetil, Collas Philippe, Küntziger Thomas
Abstract excerpt
A-kinase-anchoring protein 149 (AKAP149) is a membrane protein of the mitochondrial and endoplasmic reticulum/nuclear envelope network. AKAP149 controls the subcellular localization and temporal order of protein phosphorylation by tethering protein kinases and phosphatases to these compartments. AKAP149 also includes an RNA-binding K homology (KH) domain, the loss of function of which has been associated in other...
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