Article
A Genetic Screen To Assess Dopamine Receptor (DopR1) Dependent Sleep Regulation in Drosophila.
G3 (Bethesda, Md.) - 7 Dec 2016
Jiang Yiqin, Pitmon Elise, Berry Jack, Wolf Fred W, McKenzie Zach, Lebestky Tim J
Abstract excerpt
Sleep is an essential behavioral state of rest that is regulated by homeostatic drives to ensure a balance of sleep and activity, as well as independent arousal mechanisms in the central brain. Dopamine has been identified as a critical regulator of both sleep behavior and arousal. Here, we present results of a genetic screen that selectively restored the Dopamine Receptor (DopR/DopR1/dumb) to specific...
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