Article
A longitudinal observation of brain-derived neurotrophic factor mRNA levels in patients with relapsing-remitting multiple sclerosis.
Brain research - 23 Feb 2009
Liguori Maria, Fera Francesco, Patitucci Alessandra, Manna Ida, Condino Francesca, Valentino Paola, Telarico Pierangela, Cerasa Antonio, Gioia Maria Cecilia, di Palma Gemma, Quattrone Aldo
Abstract excerpt
This report is part of a 2-year study assessing the functional effect of Brain-Derived Neurotrophic Factor (BDNF) and its Val66Met polymorphism on a selected population of Relapsing-Remitting Multiple Sclerosis (RRMS) patients from Southern Italy. For this purpose, we measured the peripheral BDNF expression in RRMS patients compared to healthy controls. The influence of concomitant IFNbeta therapy was also...
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