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Article

The relationship between HIV-1 genome RNA dimerization, virion maturation and infectivity.

Nucleic acids research - 1 Apr 2011

Ohishi Masahisa, Nakano Takashi, Sakuragi Sayuri, Shioda Tatsuo, Sano Kouichi, Sakuragi Jun-ichi

Abstract excerpt

The relationship between virion protein maturation and genomic RNA dimerization of human immunodeficiency virus type 1 (HIV-1) remains incompletely understood. We have constructed HIV-1 Gag cleavage site mutants to enable the steady state observation of virion maturation steps, and precisely study Gag processing, RNA dimerization, virion morphology and infectivity. Within the virion maturation process, the RNA...

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Share to Dimerization
Share to gag Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Viral

Share to HIV Reverse Transcriptase

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Share to RNA, Viral

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Source

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Identifiers

PMID: 21186186
DOI: 10.1093/nar/gkq1314
PMCID: PMC3082877

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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