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Article

(TTA)n polymorphism in 3-hydroxy-3-methylglutaryl-coenzyme A and response to atorvastatin in coronary artery disease patients.

Basic & clinical pharmacology & toxicology - 1 Mar 2009

Noriega Viviana, Pennanen Christian, Sánchez María Pilar, Chiong Mario, Llancaqueo Marcelo, Lavandero Sergio, Prieto Juan Carlos

Abstract excerpt

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors have been used clinically for lowering total and low-density lipoprotein cholesterol. Interindividual pharmacological differences observed with this treatment have been attributed to genetic differences. The aim of this study was to assess the association in the low-density lipoprotein cholesterol reduction by atorvastatin and (TTA)n polymorphism in the...

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Identifiers

PMID: 19067673
DOI: 10.1111/j.1742-7843.2008.00341.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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