Article
Typing of the 3' hypervariable region of the apolipoprotein B gene: approaches, pitfalls, and applications.
Electrophoresis - 1 Mar 1993
März W, Ruzicka V, Fisher E, Russ A P, Schneider W, Gross W
Abstract excerpt
Apolipoprotein B-100 is the principal protein component of lipoproteins with very low, intermediate, and low density. The interaction of apoB-100 with low density lipoprotein (LDL) receptors is responsible for the uptake of LDL into cells. An AT-rich hypervariable region is located adjacent to the 3' end of the apoB gene. It consists of a variable number of tandemly repeated sequences (VNTR). Two approaches were...
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