Article
Sequence variants in HTRA1 and LOC387715/ARMS2 and phenotype and response to photodynamic therapy in neovascular age-related macular degeneration in populations from Israel.
Molecular vision - 1 Jan 2008
Chowers Itay, Meir Tal, Lederman Michal, Goldenberg-Cohen Nitza, Cohen Yoram, Banin Eyal, Averbukh Edward, Hemo Itzhak, Pollack Ayala, Axer-Siegel Ruth, Weinstein Orly, Hoh Josephine, Zack Donald J, Galbinur Tural
Abstract excerpt
PURPOSE: Single nucleotide polymorphisms (SNPs) in the tightly linked LOC387715/ARMS2 and HTRA1 genes have been associated with age-related macular degeneration (AMD). We tested whether these SNPs are associated with AMD in Israeli populations, if they underlie variable phenotype and response to...
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