Article
BRCA germline mutations in Jewish patients with pancreatic adenocarcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Jan 2009
Ferrone Cristina R, Levine Douglas A, Tang Laura H, Allen Peter J, Jarnagin William, Brennan Murray F, Offit Kenneth, Robson Mark E
Abstract excerpt
PURPOSE: The prognostic significance of germline BRCA1 and BRCA2 mutations in Jewish patients with pancreatic adenocarcinoma (PAC) is unknown. Our objective was to define the prevalence of BRCA1 and BRCA2 in an unselected group of Jewish patients and to compare the clinical characteristics and overall survival (OS) of patients with resected BRCA mutation-associated PAC to PAC patients without mutations. PATIENTS...
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