Article
Impact of Sixteen Established Pancreatic Cancer Susceptibility Loci in American Jews.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2017
Streicher Samantha A, Klein Alison P, Olson Sara H, Amundadottir Laufey T, DeWan Andrew T, Zhao Hongyu, Risch Harvey A
Abstract excerpt
Background: The higher risk of pancreatic cancer in Ashkenazi Jews compared with non-Jews is only partially explained by the increased frequency of BRCA1 and BRCA2 mutations in Ashkenazi Jews.Methods: We evaluated the impact of 16 established pancreatic cancer susceptibility loci in a case-control sample of American Jews, largely Ashkenazi, including 406 full-Jewish pancreatic cancer patients and 2,332...
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