The Association of Matrix Metalloproteinase-8 Promoter Genotypes in Breast Cancer.

doi:10.21873/anticanres.12459

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Article

The Association of Matrix Metalloproteinase-8 Promoter Genotypes in Breast Cancer.

Anticancer research - 1 Apr 2018

Hsiao Chieh-Lun, Liu Liang-Chih, Shih Tzu-Ching, Chuang Chin-Liang, Chen Guan-Liang, Wang Hwei-Chung, Pan Su-Yi, Shen Te-Chun, Tsai Chia-Wen, Chang Wen-Shin, Way Tzong-DER, Chung Jing-Gung, Bau DA-Tian

Abstract excerpt

BACKGROUND/AIM: The family of matrix metalloproteinases (MMPs) controls homeostasis of the extracellular matrix and their genetic polymorphisms may be associated with personal cancer susceptibility. The serum levels of MMP8 was reported to be higher in patients with breast cancer than in healthy individuals. In this study, we aimed to investigate the contribution of a polymorphism in the promoter region of MMP8...

Topics

Adult
Aged
Amino Acid Substitution
Breast Neoplasms
Case-Control Studies
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Matrix Metalloproteinase 8

Middle Aged

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Taiwan

Source

Open in PubMed

Identifiers

PMID: 29599337
DOI: 10.21873/anticanres.12459

Genes

MMP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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