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Article

Epstein–Barr virus, rapamycin, and host immune responses

20 Nov 2008

Abstract excerpt

PURPOSE OF REVIEW: To summarize recent advances that contribute to our understanding of the pathobiology of Epstein-Barr virus (EBV)-associated posttransplant lymphoproliferative disease (PTLD), the host immune response to virally infected B cells, and the molecular basis for the effects of mammalian target of rapamycin inhibitors on EBV+ B-cell lymphomas. RECENT FINDINGS: Cytogenetic and genomic analyses support...

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PMID: 19060543
DOI: 10.1097/mot.0b013e3283186ba9

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