Article
Virally targeted therapies for EBV-associated malignancies.
Oncogene - 11 Aug 2003
Israel Bruce F, Kenney Shannon C
Abstract excerpt
In Epstein-Barr virus (EBV)-positive lymphomas, the presence of the EBV genome in virtually all tumor cells, but very few normal cells, suggests that novel, EBV-targeted therapies could be used to treat these malignancies. In this paper, we review a variety of different approaches currently under development that specifically target EBV-infected cells for destruction. EBV-based strategies for treating cancer...
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