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Article

Evolution of Pseudomonas aeruginosa type III secretion in cystic fibrosis: a paradigm of chronic infection.

Translational research : the journal of laboratory and clinical medicine - 1 Dec 2008

Jain Manu, Bar-Meir Maskit, McColley Susanna, Cullina Joanne, Potter Eileen, Powers Cathy, Prickett Michelle, Seshadri Roopa, Jovanovic Borko, Petrocheilou Argyri, King John D, Hauser Alan R

Abstract excerpt

Pseudomonas aeruginosa (PA) from acute and chronic (eg, cystic fibrosis (CF)) infections differ in several respects, but they can worsen prognosis in each context. Factors that facilitate conversion from an acute to chronic phenotype are poorly understood. T3 secretion proteins are virulence factors associated with poorer outcomes in acute infections, but little is known about their role in CF. We wished to...

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Identifiers

PMID: 19059160
DOI: 10.1016/j.trsl.2008.10.003
PMCID: PMC2628760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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